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Ramucirumab (IMC-1121B): Monoclonal Antibody Inhibition of Vascular Endothelial Growth Factor Receptor-2

✍ Scribed by Jennifer Spratlin


Book ID
107546794
Publisher
Current Science Inc.
Year
2011
Tongue
English
Weight
128 KB
Volume
13
Category
Article
ISSN
1523-3790

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## Abstract The human vascular endothelial growth factor receptor‐1 (VEGFR‐1, or Flt‐1) is widely expressed in normal and pathologic tissue and contributes to the pathogenesis of both neoplastic and inflammatory diseases. In human cancer, VEGFR‐1 mediated signaling is responsible for both direct tu