Rameswaralide, a novel diterpenoid from the soft coral Sinularia dissecta

✍ Scribed by P. Ramesh; N.Srinivasa Reddy; Y. Venkateswarlu; M.Venkata Rami Reddy; D.John Faulkner

• Book ID: 104260112
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 183 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)01879-6

✦ Synopsis

Rameswaralide (4), a novel diterpene having a 5-7-6 tricyclic skeleton has been isolated along with known terpenes, afrieanene, 4,5-seco-afriean-4,5-dione, 13-elemene and isomandapamate (3) from the soft coral Sinularia dissecta from the Mandapam coast, South India. The structure and stereochemistry of rameswaralide (4) were determined using spectroscopic methods and confirmed by selective reduction of the unusually stable enol group of 4 to form dihydrorameswaralide (5).