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Raman spectroscopic studies of the DNA cro binding site conformation, free and bound to cro protein

โœ Scribed by Evertsz, Elisabeth M.; Thomas, Gerald A.; Peticolas, Warner L.


Book ID
125967370
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
920 KB
Volume
30
Category
Article
ISSN
0006-2960

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The interaction of Mg2+, Ca2+, Zn2+, and Cd2' with calf thymus DNA has been investigated by Raman spectroscopy. These spectra reveal that all of these ions, and particularly Zn2+, bind to phosphate groups of DNA, causing a slight structural change in the polynucleotide at very small metal : D N A (