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RAGE, LRP-1, and amyloid-beta protein in Alzheimer’s disease

✍ Scribed by John E. Donahue; Stephanie L. Flaherty; Conrad E. Johanson; John A. Duncan; Gerald D. Silverberg; Miles C. Miller; Rosemarie Tavares; Wentian Yang; Qian Wu; Edmond Sabo; Virginia Hovanesian; Edward G. Stopa

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
635 KB
Volume
112
Category
Article
ISSN
0001-6322

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## Abstract Research on the molecular pathogenesis of Alzheimer's disease (AD) has made great strides over the last decade. This progress is the result of protein chemical analysis of two extracellular and intracellular fibrillary lesions in AD brain conducted during the 1980s, which identified β‐a