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Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

โœ Scribed by Diefenbach, Andreas; Jensen, Eric R.; Jamieson, Amanda M.; Raulet, David H.


Book ID
109775863
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
385 KB
Volume
413
Category
Article
ISSN
0028-0836

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Identification of the rat NKG2D ligands,
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## Abstract NKG2D is a receptor expressed by NK cells and subsets of T lymphocytes. On NK cells, NKG2D functions as a stimulatory receptor that induces effector functions. We cloned and expressed two rat NKG2D ligands, both members of the RAE1 family, RAE1L and RRLT, and demonstrate that these liga