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Radiotracer method for the determination of solvent water content

โœ Scribed by Burfield, David R.


Book ID
127208789
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
413 KB
Volume
48
Category
Article
ISSN
0003-2700

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Radiotracer-based method for determining
โœ Ketai Wang; S. James Adelstein; Amin I. Kassis ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 347 KB

Ascertaining the aqueous solubility of compounds is important in the selection of drug candidates. We describe a radiotracer method for estimating water solubility of compounds that are soluble in dimethyl sulfoxide (DMSO). Various volumes of DMSO, saturated with 127 I-labeled compound and spiked wi