Radiotracer-based method for determining
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Ketai Wang; S. James Adelstein; Amin I. Kassis
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Article
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2006
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John Wiley and Sons
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French
โ 347 KB
Ascertaining the aqueous solubility of compounds is important in the selection of drug candidates. We describe a radiotracer method for estimating water solubility of compounds that are soluble in dimethyl sulfoxide (DMSO). Various volumes of DMSO, saturated with 127 I-labeled compound and spiked wi