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Radiotherapy to control CNS lymphomatoid granulomatosis: A case report and review of the literature

✍ Scribed by Petrella, Teresa M.; Walker, Irwin R.; Jones, Glenn W.; Leber, Brian

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 18 KB
Volume: 62
Category: Article
ISSN: 0361-8609
DOI: 10.1002/(sici)1096-8652(199912)62:4<239::aid-ajh7>3.0.co;2-u

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✦ Synopsis

Lymphomatoid granulomatosis (LG) is an uncommon but potentially fatal disease. The disease primarily involves the lungs; however, skin, renal, and central nervous system (CNS) are seen in varying proportions. Neurological involvement occurs in one third of the patients, and confers a worse prognosis. The use of radiotherapy to treat CNS involvement in LG has not been well studied. We report a case of a 33-year-old man with multiple CNS lesions treated successfully with radiotherapy and review 6 other cases in the literature using similar treatment. These cases support the use of radiotherapy for CNS involvement in LG. Am.

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