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Radiosynthesis of [18F] N-(3-Fluoropropyl)-2-β-Carbomethoxy-3-β-(4-Bromophenyl) Nortropane and the regional brain uptake in non human primate using PET

✍ Scribed by Thomas Chaly; R.M. Baldwin; John L. Neumeyer; Matthew J. Hellman; Vijay Dhawan; Pradeep K. Garg; Gilles Tamagnan; Julie K. Staley; Mohammed S. Al-Tikriti; Yankun Hou; Sami S. Zoghbi; Xiao-Hui Gu; R. Zong; David Eidelberg

Book ID
117687990
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
199 KB
Volume
31
Category
Article
ISSN
0969-8051

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Simplified synthesis of N-(3-[18F]fluoropropyl)-2β-carbomethoxy-3β-(4-fluorophenyl)nortropane ([18F]β-CFT-FP) using [18F]fluoropropyl tosylate as the labelling reagent
✍ Teija Koivula; Outi Perhola; Eeva-Liisa Kämäräinen; Tiina Lipponen; Jouko Vepsäl 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 114 KB

A synthesis method has been developed for the labelling of N-(3-[ 18 F]fluoropropyl)-2b-carbomethoxy-3b-(4-fluorophenyl)nortropane ([ 18 F]b-CFT-FP), a potential radioligand for visualization of the dopamine transporters by positron emission tomography. The two-step synthesis includes preparation of