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Radiosynthesis and biological evaluation of99mTcN-sitafloxacin dithiocarbamate as a potential radiotracer forStaphylococcus aureusinfection

✍ Scribed by Syed Qaiser Shah; Aakif Ullah Khan; Muhammad Rafiullah Khan


Publisher
Springer
Year
2010
Tongue
English
Weight
334 KB
Volume
287
Category
Article
ISSN
1588-2780

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✍ Jie Lu; Dejing Kong; Hongmei Jia; Winnie Deuther-Conrad; Peter Brust; Xuebin Wan 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 127 KB

## Abstract The goal of this study is to develop a novel ^99m^Tc‐labeled σ receptor imaging agent. Potassium 4‐(cyclohexylpiperazin‐1‐yl)‐dithioformate, **2**, and the corresponding rhenium complex, **ReN‐2**, were synthesized and characterized. **ReN‐2** possessed moderate affinity toward σ~1~ (K~