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Radiosynthesis and autoradiographic evaluation of [11C]NAD-299, a radioligand for visualization of the 5-HT1A receptor

✍ Scribed by Johan Sandell; Christer Halldin; Håkan Hall; Seth-Olov Thorberg; Tom Werner; Daniel Sohn; Göran Sedvall; Lars Farde


Book ID
117688339
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
823 KB
Volume
26
Category
Article
ISSN
0969-8051

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Radiosynthesis and in vivo evaluation of
✍ Frédéric Dollé; Héric Valette; Stéphane Demphel; Christine Coulon; Michelle Otta 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB

## Abstract [2‐(3,4‐Dihydro‐1H‐isoquinolin‐2‐yl)‐pyridin‐4‐yl]‐dimethylamine, Ro‐647312 (**1**) represents a new novel class of NR1/2B subtype selective NMDA ligand. Ro‐647312 has been radiolabelled with carbon‐11 using [^11^C]methyl triflate from the __nor‐__methyl compound **2**. The reaction was