Radiosensitization of human tumor cells by alpha-difluoromethylornithine
โ Scribed by A. Courdi; G. Milano; M. Bouclier; C. M. Lalanne
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- French
- Weight
- 440 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
โฆ Synopsis
ALPHA-DIFLUOROMETHY LORNITHINE
CIRD (Centre International de Recherches
The effect of polyamine depletion on the radiosensitivity of a human tumor cell line was investigated. CAL 18 A cells, derived from a breast carcinoma, were incubated with alpha-difluoromethylornithine (DFMO)
a specific and irreversible inhibitor of ornithine decarboxylase (ODC)at a I mw or 10 -mM concentra-
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