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Radiosensitivity and differentiation of ganglion cells within fetal mouse retinal explants in vitro

✍ Scribed by Neil R. Smalheiser; Stanley M. Crain

Book ID
119100897
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
786 KB
Volume
13
Category
Article
ISSN
0165-3806

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## Abstract Inositol 1,4,5‐trisphosphate receptors (IP~3~R) are ligand‐gated intracellular Ca^2+^channels that mediate release of Ca^2+^ from intracellular stores into the cytosol on activation by second messenger IP~3~. Similarly, IP~3~R mediated changes in cytosolic Ca^2+^ concentrations control