Radiosensitive gene therapy through imRNA expression for silencing manganese superoxide dismutase

Radioprotective gene therapy through ret

Radioprotective gene therapy through retroviral expression of manganese superoxide dismutase

✍ Thomas D. Southgate; Victoria Sheard; Michael D. Milsom; Timothy H. Ward; Robert 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 279 KB

## Abstract ## Background Radiotherapy for the control of cancer, either alone or in conjunction with chemotherapy, is often limited by normal tissue toxicity including haematopoietic toxicity. Exposure of cells to ionizing radiation leads to the formation of reactive oxygen species that are assoc