Radionuclide bone scan, radiographic bone survey, and alkaline phosphatase. Studies of limited value in asymptomatic patients with ovarian carcinoma
✍ Scribed by Fred A. Mettler Jr; James H. Christie; Neil E. Crow Jr; Jose F. Garcia; Jeffrey D. Wicks; Sue A. Bartow
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 222 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Bone scans or skeletal surveys were obtained in 104 patients with ovarian carcinoma. No metastases were identified at staging in the 43 patients with Stage 1 or I1 disease. Four patients in the entire series had osseous metastases. Three of the 40 patients with Stage 111 epithelial ovarian carcinoma had osseous metastases at the time of staging. All of these were Grade 111 lesions. One Stage I, Grade I11 patient demonstrated osseous metastases two years after initial diagnosis. None of the four patients with osseous metastases had an elevated alkaline phosphatase; three of the four had bone pain. Based on these results, it is suggested that radiographic bone survey and radionuclide bone scans are not indicated as screening procedures in asymptomatic patients with ovarian carcinoma.