Radiolysis of binary mixtures. Part VIII. Tritium Labelling by direct radiation synthesis. The methanol-benzene system
✍ Scribed by A. Ekstrom; J. L. Garnett
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- French
- Weight
- 453 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
A novel synthesis of tritiated compounds is reported using the direct irradiation of an aromatic-aliphatic mixture, one of the components of which is labelled with tritium. The irradiation of the methanoltritiated benzene system has been used to illustrate the principle of the technique. The gamma irradiation of methanolic solutions of tritiated benzene yields the following tritiated scavenging products, some of which are specijically labelled under certain conditions : anisole; 1,3 -and 1,4-cyclohexadienes; 2,5-phenylcyclohexadiene; 1,3and 1,4-cyclohexadiene-methanols. The potential of the method as a general tritium labelling tool is discussed and compared with conventional procedures. Although the absolute yields of the Iabelled products from direct irradiation are small for relatively large total radiation doses (megarads), scavenging by non-labelled parent material can be used to give large chemical yields $required. The predominant advantage of the present method is that compounds labelled in specijic positions with tritium can be obtained in a onestep chemical process whereas this synthesis may be dificult by other conventional labelling methods.
* G value --number of molecules formed per 100 electron volts of energy absorbed per gram of solution.