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Radiologic evaluation of the thymus in juvenile myasthenia gravis

✍ Scribed by A. S. Thurmond; R. C. Brasch


Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
589 KB
Volume
7
Category
Article
ISSN
0301-0449

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In 5-10% of all patients with typical generalised myasthenia gravis (MG), serum antibody to the acetylcholine receptor (AChR) is undetectable. To determine whether these represent a distinct subgroup, we have compared the thymuses of 14 seronegatives, 70 seropositives and 12 non-myasthenic controls.

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The results of thymectomy carried out in 150 cases of myasthenia gravis are discussed. In a group of 123 cases followed for 1 to 5 years after the operation, full remission was observed in 24.4% of cases, significant improvement in 36.6%, slight improvement in 24.4% and no improvement in 8.1%, while