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Radiolabeled RGD-DTPA-Tyr 3 -Octreotate for Receptor-Targeted Radionuclide Therapy

✍ Scribed by Bernard, Bert; Capello, Astrid; van Hagen, Martin; Breeman, Wout; Srinivasan, Ananth; Schmidt, Michelle; Erion, Jack; van Gameren, Arthur; Krenning, Eric; De Jong, Marion


Book ID
120185046
Publisher
Mary Ann Liebert
Year
2004
Tongue
English
Weight
221 KB
Volume
19
Category
Article
ISSN
1084-9785

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We have evaluated the potential usefulness of radiolabelled [DTPA 0 ,Tyr 3 ]octreotide and [DOTA 0 ,Tyr 3 ]octreotide as radiopharmaceuticals for somatostatin receptor-targeted scintigraphy and radiotherapy. In vitro somatostatin receptor binding and in vivo metabolism in rats of the compounds were