Radioiodination of monoclonal antibodies d612 and 17-1a with 3-lodophenylisothiocyanate and their biodistribution in tumor-bearing nude mice

Tumor targeting properties of monoclonal

Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head-and-neck cancer xenografts

✍ Iris Verel; Karl-Heinz Heider; Miranda Siegmund; Elínborg Ostermann; Erik Patzel 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 160 KB

## Abstract The CD44 protein family consists of isoforms with tissue‐specific expression, which are encoded by standard exons and up to 9 alternatively spliced variant exons (v2–v10) of the same gene. The murine MAbs U36 and BIWA‐1, directed against overlapping epitopes within the v6 region of CD44