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Radioimmunotherapy of human glioma xenografts in nude mice by indium-111 labelled internalising monoclonal antibody

โœ Scribed by T Saga; H Sakahara; Y Nakamoto; N Sato; S Zhao; T Aoki; S Miyatake; Y Namba; J Konishi

Book ID
117666779
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
104 KB
Volume
35
Category
Article
ISSN
0959-8049

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111Indium-labeled monoclonal antibody K1
111Indium-labeled monoclonal antibody K1: Biodistribution study in nude mice bearing a human carcinoma xenograft expressing mesothelin
โœ Raffit Hassan; Chuanchu Wu; Martin W. Brechbiel; Inger Margulies; Robert J. Krei ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 68 KB

The monoclonal antibody (MAb) K1 is a murine IgG 1 that recognizes mesothelin, a differentiation antigen present on mesothelium which is highly expressed on cancers derived from mesothelium, including most ovarian cancers and epithelioid mesotheliomas. MAb K1 was conjugated to 2-(pisothiocyanatobenz