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Radioimmunoassay of ricin A- and B-chains applied to samples of ricin A-chain prepared by chromatofocusing and by DEAE Bio-Gel A

✍ Scribed by Ramakrishnan, S.; Eagle, Merryn R.; Houston, L.L.

Book ID
123526467
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
573 KB
Volume
719
Category
Article
ISSN
0304-4165

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Mannose receptor dependent uptake of ric
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✍ Fabio Riccoboni; Maria L. Fiani πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 526 KB

The ricin A chain, the toxic subunit of ricin, consists of two forms which differ in sugar content. The major component A1 contains one high mannose chain while the minor component A2 contains an additional high mannose chain. Endocytosis of this toxin occurs in macrophages via the mannose receptor.