Radiofrequency ablation of head and neck tumors: Dramatic results from application of a new technology
β Scribed by Randall P. Owen; Thanjavur S. Ravikumar; Carl E. Silver; Jonathan Beitler; Scott Wadler; Jacqueline Bello
- Book ID
- 102233307
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 228 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1043-3074
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β¦ Synopsis
Abstract
Background
Radiofrequency ablation (RFA) is a new treatment modality used over the past decade predominantly in the treatment of unresectable liver tumors. We find no prior reported series on the use of RFA for malignant tumors of the head and neck.
Methods
Four patients with recurrent tongue tumors not amenable to standard surgical or radiation therapy were treated with RFA administered transorally, endoscopically, or percutaneously.
Results
There was no perioperative mortality. Significant palliation was achieved consisting of substantial reduction in tumor size and alleviation of tumorβinduced pain. One patient has survived for 8 months with no progression of tumor. Three patients had complications, including line sepsis, pneumonia, and enlargement of an orocutaneous fistula.
Conclusions
RFA was relatively straightforward to apply, achieved substantial palliation, and was associated with minimal perioperative morbidity and no mortality. It might easily be combined with other therapies such as chemotherapy, immunotherapy, or radiation. Further investigation is necessary and ongoing. Β© 2002 Wiley Periodicals, Inc. Head Neck 24: 754β758, 2002
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## Abstract ## Background. Radiofrequency ablation (RFA) is a minimally invasive tumor destruction technique and can provide the antigen source initiating tumor immunity. However, induced immune response is weak and requires additional immunotherapy for optimized RFA treatment against cancer. ##