✦ LIBER ✦

Radiofluorination and biological evaluation ofN-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2receptors

✍ Scribed by Rodrigo Teodoro,Rareş-Petru Moldovan…

Book ID: 121619251
Publisher: Springer-Verlag
Year: 2013
Tongue: English
Weight: 642 KB
Volume: 3
Category: Article
ISSN: 2191-2858
DOI: 10.1186/2191-2858-3-11

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and preliminary biological eva

Synthesis and preliminary biological evaluation of [123I]Me2Pyr, a new potential ligand for imaging of central cannabinoid CB1 receptors

✍ P. Gielow; P. Klinge; W.H. Knapp; G. Berding 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 279 KB

Synthesis and biological evaluation of S

Synthesis and biological evaluation of S-[11C]methylated mercaptoimidazole piperazinyl derivatives as potential radioligands for imaging 5-HT1A receptors by positron emission tomography (PET)

✍ Raquel Garcia; Catarina Xavier; António Paulo; Isabel Santos; Torsten Kniess; R. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 157 KB

The novel 2-mercaptoimidazole derivatives, 1-[4-((2-methoxyphenyl)-1-piperazinyl)butyl]-2-mercaptoimidazole (3) and methyl[4-((2-methoxyphenyl)-1-piperazinyl))butyl] (2-mercapto-1-methylimidazol-5-yl)methanamide ( 8), were efficiently labelled with 11 C through methylation of the thioketone function

Synthesis of 1-(2,4-dichlorophenyl)-4-cy

Synthesis of 1-(2,4-dichlorophenyl)-4-cyano-5-(4-[11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([11C]JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4-[11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([11C]JHU75575) as potential radioligands for PET imaging of cerebral cannabinoid receptor

✍ Hong Fan; Hayden T. Ravert; Daniel P. Holt; Robert F. Dannals; Andrew G. Horti 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 183 KB

## Abstract Two novel ligands for cerebral cannabinoid receptor (CB1), 1‐(2,4‐dichlorophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75528) and 1‐(2‐bromophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75575)