The proteasome and its role in the degra
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Tobias Jung; Tilman Grune
📂
Article
📅
2008
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John Wiley and Sons
🌐
English
⚖ 277 KB
## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi