Radical-initiated polyolefinic cyclizations in condensed cyclopentanoid synthesis. Total synthesis of (±)-Δ9(12)-capnellene

Consecutive Application of the α-Alkynon

Consecutive Application of the α-Alkynone Cyclization: Total Synthesis of (±)-Δ9(12)-Capnellene

✍ Joan Huguet; Martin Karpf; André S. Dreiding 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 German ⚖ 576 KB

## Abstract The synthesis of the (±)‐form of the marine sesquiterpene (–)‐Δ^9(12)^‐capnellene (**1**) by double application of the __a__‐alkynone cyclization is described. Starting with 2, 2, 5‐trim ethylcyclopentanone (**2**), the elaboration of the tricyclo [6.3.0.0^2,6^]undecane C‐skeleton of **