Radical Carboaminoxylation with Subsequent Pd-Catalyzed Intramolecular Allylation for the Construction of Five- and Six-Membered Carbocycles.

ChemInform Abstract: Stereochemistry. Pa

ChemInform Abstract: Stereochemistry. Part 89. A Highly Stereoselective One-Pot Tandem Consecutive 1,4-Addition-Intramolecular 1,3-Dipolar Cycloaddition Strategy for the Construction of Functionalized Five- and Six-Membered Carbocycles.

✍ I. N. N. NAMBOOTHIRI; A. HASSNER; H. E. GOTTLIEB 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Strategy for the Construction of Functionalized Five-and Six-Membered Carbocycles. -Conjugate addition of the Grignard reagents (II) and (IV) to the nitro olefins (I) leads to the intermediate formation of nitronates, which are trapped as silyl nitronates and subsequently cyclized by intramolecular