Radical Allylation with α-Branched Allyl Sulfones
✍ Scribed by Nicolas Charrier; Samir Z. Zard
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 287 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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## Abstract The two‐step alkylation of phenyl prop‐2‐enyl sulfone (1) with protected ω‐bromoalkanols and 1‐iodoalkanes (→3; see __Scheme 1__) followed by a Pd‐catalyzed desulfonylation with LiBH~4~ affords a 96:4 mixture of vinylbranched, protected alcohols and corresponding ethylidene‐branched iso