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Radical additions of simple piperazine-25-diones

✍ Scribed by Christina L.L. Chai; Dennis M. Page

Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
245 KB
Volume
34
Category
Article
ISSN
0040-4039

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✦ Synopsis

The polar character of a simple piperazine-2,S-dione was investigated under intermolecular radical addition conditions. 'Ihe results indicate that captodative radical of this kind neither show extreme nucleophilic nor electrophilic tendencies.

The formation of new carbon-carbon bonds employing small molecules as building blocks is crucial in organic synthesis and free radical chemistry has provided viable methods for such carbon-carbon chain extensions.2" The intermolecular addition of radicals to alkenes remains an important and versatile procedure even though problems can be associated with radical reactivity and selectivityP.4 Alkyl radicals are generally

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