DNA Repair capacity and cisplatin sensit
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Beate KΓΆberle; Keith A. Grimaldi; Andrew Sunters; John A. Hartley; Lloyd R. Kell
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Article
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1997
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John Wiley and Sons
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French
β 96 KB
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Metastatic testicular germ cell tumours can be cured using cisplatin-based combination chemotherapy. To investigate the role of DNA repair in cisplatin sensitivity, we measured the formation and removal of cisplatin adducts in the whole genome and in specific genomic regions in 3 testis and 3 bladde