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Radiation response in 10 high-grade human soft tissue sarcoma xenografts to photons and fast neutrons

โœ Scribed by V. Budach; M. Stuschke; W. Budach; M. Molls; H. Sack


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
286 KB
Volume
19
Category
Article
ISSN
0360-3016

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BACKGROUND. P-glycoprotein-mediated drug efflux has been implicated as an important mechanism of multidrug resistance (MDR) in cancer. Its role in chemotherapy resistance in soft tissue sarcoma is unclear. ## METHODS. Tumor specimens prior to and following neoadjuvant chemotherapy from 29 cases o