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Radiation-induced sarcoma of the breast in a female adolescent. Case report with histologic and therapeutic considerations

✍ Scribed by R. Squire; A. Bianchi; S. M. Jakate


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
477 KB
Volume
61
Category
Article
ISSN
0008-543X

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✦ Synopsis


A 14-year-old girl developed a radiation-induced sarcoma of the left breast after successful combined surgical and radiation therapy of a left adrenal carcinoma when she was 9 months old. The breast lesion was histologically described as a stromal sarcoma with fibrosarcomatous and myxosarcomatous areas. The second primary lesion and local recurrence of this was treated with surgery. At each recurrence the tumor became more aggressive both clinically and histologically, and eventually proved fatal.