Radiation-Induced Metabolome Delineates Glioblastoma and Glioblastoma Stem Cell Subtypes and Correlate With Their Relative Radiation Sensitivities

Endothelial cells co-cultured with wild-

Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis

✍ Nikolai N. Khodarev; Edwardine Labay; Thomas Darga; Jianqing Yu; Helena Mauceri; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 166 KB

## Abstract We performed expressional profiling of isogenic glioblastoma cell lines U87‐Lux8 and U87‐175.4. These cell lines differ in that U87‐Lux8 expresses wild‐type p53 and U87‐175.4 expresses a dominant‐negative p53 (175^His^ mutation). DNA array analysis and real‐time PCR measurements demonst