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Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis

✍ Scribed by Olaug Kristin Rødningen; Anne-Lise Børresen-Dale; Jan Alsner; Trevor Hastie; Jens Overgaard


Book ID
118496992
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
112 KB
Volume
86
Category
Article
ISSN
0167-8140

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## Abstract To better understand the molecular basis of radiation‐induced osteosarcoma (OS), we performed global gene expression profiling of rat OS tumors induced by the bone‐seeking alpha emitter ^238^Pu, and the expression profiles were compared with those of normal osteoblasts (OB). The express