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Radiation-induced fibrosis: A rationale for Smad3 inhibition

✍ Scribed by Judy W. Lee; Richard H. Zoumalan; Pierre Saadeh

Book ID: 116814855
Publisher: SAGE Publications
Year: 2009
Tongue: English
Weight: 74 KB
Volume: 141
Category: Article
ISSN: 0194-5998
DOI: 10.1016/j.otohns.2009.06.171

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## Abstract Transforming growth factor‐β (TGF‐β) is a multifunctional growth factor, affecting cell proliferation, apoptosis, and extracellular matrix homeostasis. It also plays critical roles in mammary gland development, one of which involves inhibition of the expression of milk proteins, such as