Radiation-induced chromosome aberrations and sister chromatid exchanges in lymphocytes from patients with tuberous sclerosis
β Scribed by Sumio Iijima; Makoto Higurashi; Tatsuya Takeshita; Yoko Kawasaki; Masuko Funahashi
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 232 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1435-232X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Peripheral blood lymphocytes from three patients with Down syndrome (DS; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (SCEs). Cells in G0 were exposed to bleomycin (20-100 micrograms/ml) fo
The incidence of structural chromosome aberrations and the rate of sister chromatid exchanges (SCE) was investigated in lymphocyte cultures from a patient with typical Fanconi's anemia and his parents. The rate of SCEs was found to be normal. In experiments with the alkylating agent Trenimon the SCE
Structural, and numeric chromosome aberrations (CA), sisterchromatid exchange (SCE), phytohe magglutinin stimulation (ti), proliferative rate index (PRI), and UV light-induced unscheduled DNA-synthesis (UDS) were investigated in peripheral blood lymphocytes (PBL) of 48 historical controls ("Controls