Radiation-induced apoptosis in human ovarian carcinoma cells growing as a monolayer and as multicell spheroids

Lonidamine as a modulator of taxol activ

Lonidamine as a modulator of taxol activity in human ovarian cancer cells: effects on cell cycle and induction of apoptosis

✍ Linda Orlandi; Nadia Zaffaroni; Alessandra Bearzatto; Raffaella Villa; Cinzia De 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 188 KB 👁 2 views

The ability of lonidamine (LND), an energolytic derivative of indazole-carboxylic acid, to modulate the cytotoxicity of Taxol (TX) was investigated in the A2780 human ovarian cancer cell line. Different cytotoxicity results were obtained as a function of treatment schedule. Specifically, TX followed