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Radiation-enhanced hepatocyte growth factor secretion in malignant glioma cell lines

✍ Scribed by Chu Sheng-hua; Ma Yan-bin; Zhu Zhi-an; Zhang Hong; Feng Dong-fu; Li Zhi-qiang; Yuan Xian-hou


Book ID
116895050
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
317 KB
Volume
68
Category
Article
ISSN
0090-3019

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A human malignant glioma cell line, U-251 Mg, cultured under serum free conditions, was shown to produce a growth factor for BALB/c 3T3 cells (glioma-derived growth factor-I, GDGF-1). The biological activity of GDGF-1 resided in a heat-and acid-resistant protein with a molecular weight (MW) of 25 kD