✦ LIBER ✦

Radiation biology of lung cancer

✍ Scribed by Francis J. Sullivan; James Carmichael; Eli Glatstein; Dr. James B. Mitchell

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 699 KB
Volume: 63
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.240630510

No coin nor oath required. For personal study only.

✦ Synopsis

The enormous problem that is lung cancer still defies satisfactory therapeutic strategy. This article summarizes some of the more important laboratory efforts directed at understanding the biology of this complex disease. The radiation sensitivities of established lung cancer cell lines are outlined. The effect of radiation dose rate and chemotherapy is explored. The emerging biology of oncogenetic alterations is explored as it relates to radiation sensitivity in general, and lung cancer in particular. Finally, novel therapeutic approaches including photodynamic therapy are introduced.

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