RACK1: a novel substrate for the Src protein-tyrosine kinase
β Scribed by Chang, Betty Y; Harte, Rachel A; Cartwright, Christine A
- Book ID
- 110067393
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 77 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have recently determined that -Ile-Tyr- were the two critical residues as a peptide substrate for p60c-src protein tyrosine kinase (Lou, Q. et al., Lett. Peptide Sci., 1995, 2, 289). Here, we report on the design and synthesis of a secondary 'one-bead, one-compound' combinatorial peptide library
## ABSTRACT The peripheral nonβreceptor tyrosine kinase oncoprotein, vβSrc, has pleiotropic effects. It is a mitogen for quiescent cells, substituting for both competence and progression factorβmediated signals but it also induces cellular morphological transformation. We are dissecting the activit
Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo