Racing for cell immortality, telomeres, telomerase, and the measure of health
β Scribed by Y. E. Yegorov; A. V. Zelenin
- Book ID
- 110213748
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 128 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1062-3604
No coin nor oath required. For personal study only.
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Telomerase RNA component (TERC) and telomerase reverse transcriptase (TERT) function together to elongate telomeres and to protect chromosomal ends. Recent studies have discovered that overexpression of telomerase's TERT subunit promoted epidermal stem-cell mobilization, hair growth and stem-cell pr
## BACKGROUND. Telomerase is a ribonucleoprotein that synthesizes telomeres. It is detected in more than 85% of samples obtained from cancer tissues, including urologic neoplasia. The authors determined telomerase activity semiquantatively and in-cell telomerase activity in exfoliated urothelial c