Racemization of R-2-amino-1-butanol catalyzed by a fixed-bed Raney cobalt catalyst

✍ Scribed by Yuecheng Zhang; Guoyi Bai; Yang Li; Xilong Yan; Ligong Chen

• Book ID: 104057059
• Publisher: Elsevier Science
• Year: 2006
• Tongue: English
• Weight: 497 KB
• Volume: 255
• Category: Article
• ISSN: 1381-1169
• DOI: 10.1016/j.molcata.2006.04.033

✦ Synopsis

Racemization of R-2-amino-1-butanol proceeded effectively over a fixed-bed Raney cobalt catalyst in a continuous fixed-bed reactor under the hydrogen pressure in the range of 2.0-6.0 MPa. The performance of a fixed-bed Raney cobalt catalyst was compared with that of a pulverous Raney cobalt catalyst. The catalysts were characterized by X-ray photoelectron spectroscopy (XPS), X-ray diffractometry (XRD), environment scanning electron microscopy (ESEM) and N 2 adsorption measurement (BET). The activity and stability of the fixed-bed Raney cobalt catalyst and the effects of concentration, temperature and hydrogen pressure were examined. Racemic 2-amino-1-butanol was obtained with a total yield of over 76% under the optimum reaction conditions. Thus, an effective process for the racemization of R-2-amino-1-butanol has been established.