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Racemization and geometrical isomerization of (-)-(R,R)-cyclopropane-1,2-2H2

โœ Scribed by Cianciosi, Steven J.; Ragunathan, N.; Freedman, Teresa B.; Nafie, Laurence A.; Baldwin, John E.


Book ID
126159283
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
438 KB
Volume
112
Category
Article
ISSN
0002-7863

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A short synthesis of (1S,2R)- and (1R,2R
โœ Jens Nieschalk; David O'Hagan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 350 KB

A straightforward three step route to (1S,2R)-and (1R,2R)-[2H]-glycerols la and lb is reported. The key asymmetric step involves an AD-mix-l~ dihydroxylation on deuterium labelled Z-and E-allyl benzoates 4a and 4b. The route should facilitate the use of [2H]-glycerols la-ld in high enantiomeric puri