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Race, biochemical disease recurrence, and prostate–specific antigen doubling time in the SEARCH database

✍ Scribed by Isaac Powell

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 45 KB
Volume: 110
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.23045

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✦ Synopsis

In their study in the current issue of Cancer, Hamilton et al. attempt to resolve conflicting data regarding prostate cancer and racial outcomes. The most interesting findings include a significantly younger population of black men with higher prostate–specific antigen levels, similar tumor grade, and less extracapsular extension, yet with a higher rate of biochemical disease recurrence compared with white men. Recent genetic studies have reported that variants on chromosome 8q24 and CYP3A4 on chromosome 7 are associated with aggressive prostate cancer in young black men.

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