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Rac1 GTPase regulates gene transcription of matrix metalloproteinase-1 and cell motility induced by IL-1beta in human pancreatic stellate cells

✍ Scribed by Hozawa, Shigenari; Suzuki, Haruko; Sakuma, Toshiyuki; Watanabe, Kenichi; Ueno, Hikaru; Shintani, Yutaka; Mine, Tetsuya

Book ID
122476902
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
238 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Expression of 12 matrix metalloproteinases (MMPs) after exposure of human melanoma cell lines C32TG and Mewo to nitric oxide (NO) was investigated by the reverse transcription‐polymerase chain reaction. Expression of the mRNA of MMP‐1, ‐3, ‐10 and ‐13 in C32TG cells was transcriptionall