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R(−)2-fluoro-n-n-propylnorapomorphine: A very potent and D2-selective dopamine agonist

✍ Scribed by R.J. Baldessarini; N.S. Kula; Y. Gao; A. Campbell; J.L. Neumeyer


Book ID
118956404
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
311 KB
Volume
30
Category
Article
ISSN
0028-3908

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## Abstract 2‐Fluoronorapomorphine, the PET labelling precursor to 2‐fluoro‐__N__‐[^11^C]propylnorapomorphine, was prepared in 13 steps from codeine in a total yield of 10 %. Codeine was converted in four steps into __N__‐benzylnorcodeine which was oxidised by using the Swern protocol. Subsequent a