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R1615P: A novel mutation in ABCA1 associated with low levels of HDL and type II diabetes mellitus

✍ Scribed by Danish Saleheen; Aisha Nazir; Shaheen Khanum; Shajjia R. Haider; Philippe M. Frossard


Book ID
116544171
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
268 KB
Volume
110
Category
Article
ISSN
0167-5273

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We showed previously that a mutation in the mitochondria1 tRNAL"(UUR' gene at position 3243 associates with maternally inherited diabetes and deafness (MIDD). This mutation shows heteroplasmy in DNA from peripheral blood and other tissues. To examine whether heteroplasmy levels in peripheral blood D