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R-spondin1 is required for normal epithelial morphogenesis during mammary gland development

✍ Scribed by Sead Chadi; Laurine Buscara; Christine Pechoux; José Costa; Johann Laubier; Marie-Christine Chaboissier; Eric Pailhoux; Jean-Luc Vilotte; Eric Chanat; Fabienne Le Provost


Book ID
116299383
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
423 KB
Volume
390
Category
Article
ISSN
0006-291X

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The APC tumor suppressor is required for
✍ Jenifer R. Prosperi; Kimberly R. Becher; Tara A. Willson; Margaret H. Collins; D 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 976 KB

## Abstract Inactivation of the adenomatous polyposis coli (APC) tumor suppressor has been associated with mammary tumorigenesis in mouse models and through epidemiological studies of human breast cancers, but the normal role for APC in mammary development has not been thoroughly characterized. We