R factor elimination by inhibitors of thymidhlate synthetase (fluorodeoxyuridine and showdomycin) and the occurrence of single strand breaks in plasmid DNA

Reproducibility of basal and induced DNA

Reproducibility of basal and induced DNA single-strand breaks detected by the single-cell gel electrophoresis assay in human peripheral mononuclear leukocytes

✍ O. Holz; R. Jörres; A. Kästner; T. Krause; H. Magnussen 📂 Article 📅 1995 🏛 Springer-Verlag 🌐 English ⚖ 633 KB

The aim of the reported study was to investigate the reproducibility of the single-cell gel electrophoresis (SCGE) assay in the determination of DNA singlestrand breaks (SS Bs) and to estimate the statistical requirements when the SCGE assay is used for the detection of genotoxicity in humans In hum