The title compound, C~9~H~15~NOS, was prepared by the reduction of 2-thienyl 2-(dimethylamino)ethyl ketone hydrochloride with sodium borohydride. In the crystal structure, O—H...N hydrogen bonds link pairs of molecules into centrosymmetric dimers.
(R)-3-Hydroxy-N,N-dimethyl-3-(2-thienyl)propanamine
✍ Scribed by Tao, Xiao ;Bin, Xu ;Zhu, Hong-Jun ;Yuan, Lin ;Wang, Jin-Tang
- Publisher
- International Union of Crystallography
- Year
- 2006
- Tongue
- English
- Weight
- 141 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The title compound, C 9 H 15 NOS, was prepared by asymmetric synthesis from 3-dimethylamino-1-(2-thienyl)propan-1-one hydrochloride. In the molecule, the essentially planar CCCN chain makes a dihedral angle of 16.7 (3) with the thiophene ring. In the crystal structure, molecules are linked by O-HÁ Á ÁN hydrogen bonds to form a chain along the b axis.
📜 SIMILAR VOLUMES
The title compound, also known as salicifoline chloride, C~12~H~20~NO~2~ ^+^·Cl^−^, was isolated from __Eniconsanthum membranifolium__ J. Sinclair for X-ray analysis. Salicifoline is hydrogen bonded to a chloride ion __via__ the OH group.
The molecular structure of (I), showing 50% probability displacement ellipsoids and the atom-numbering scheme.
The title compound, C 17 H 17 NO 4 , was synthesized by the Reformatsky reaction of 1,3-benzodioxole-5-carbaldehyde and N-methyl-N-phenylcarbamic bromide. The two benzene rings are inclined at a dihedral angle of 50.6 (3) .