Quinonoid dihydrobiopterin, an important metabolic intermediate of biopterin cofactor in the aromatic hydroxylation of amino acids

Differences in the metabolism of the aro

Differences in the metabolism of the aromatic amino acid hydroxylase cofactor, tetrahydrobiopterin, in mutant mice with neurological and immunological defects

✍ David S. Duch; Seaton W. Bowers; Jeffrey H. Woolf; Muriel T. Davisson; Lois J. M 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 595 KB

Tetrahydrobiopterin (BH4) levels and GTP cyclohydrolase activity (GTP-CH) were measured in tissues from mutants and controls of 24 different mouse strains to identify mutants that might be suitable models for diseases which are characterized by a deficiency of the biopterin cofactor, such as parkins