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Quinidine Thiourea-Catalyzed Aldol Reaction of Unactivated Ketones: Highly Enantioselective Synthesis of 3-Alkyl-3-hydroxyindolin-2-ones

✍ Scribed by Dr. Qunsheng Guo; Dr. Mayur Bhanushali; Prof. Dr. Cong-Gui Zhao

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
307 KB
Volume
122
Category
Article
ISSN
0044-8249

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✦ Synopsis

Scheme 1. Aldol reactions involving the enamine or enolate intermediates. Scheme 2. Catalysts screened for the cross-aldol reaction of isatin and acetone [Ar = 3,5-(CF 3 ) 2 C 6 H 3 ].

📜 SIMILAR VOLUMES

ChemInform Abstract: Organocatalytic Asy
ChemInform Abstract: Organocatalytic Asymmetric Aldol Reaction of Ketones with Isatins: Straightforward Stereoselective Synthesis of 3-Alkyl-3-hydroxyindolin-2-ones.
✍ Jia-Rong Chen; Xiao-Peng Liu; Xiao-Yu Zhu; Liang Li; Yong-Feng Qiao; Jian-Ming Z 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 60 KB 👁 1 views

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